구강소독제의 적용 시간 및 기계적 세척 여부에 따른 타액 내 세균 수의 감소 효과
Salivary Bacterial Counts on Application Time of Oral Antiseptic Agents and Mechanical Irrigation
임형섭, 김재진, 김학균, 김미자,
소속 상세정보
임형섭 ( Lim Hyong-Sup ) - 조선대학교 치의학전문대학원 구강악안면외과학교실
김재진 ( Kim Jae-Jin ) - 충남대학교 의학전문대학원 구강악안면외과학교실
김학균 ( Kim Hak-Kyun ) - 충남대학교 의학전문대학원 구강악안면외과학교실
김미자 ( Kim Mi-Ja ) - 배재대학교 간호학과
KMID : 1036320130350030155
Abstract
Purpose: The purpose of this study is to establish the acceptable intraoral application time of antiseptic agents and evaluate the effect of mechanical irrigation.
Methods: A total of 80 subjects were selected for this study. Saliva secreted at the resting state was taken. The subjects were divided into 8 experimental groups, and kept 10% povidone-iodine (PVI) or 0.2% chlorhexidine gluconate (CHX) for 20 or 40 seconds in their oral cavity with/without irrigation of the oral cavity with sterilized normal saline, respectively. Then, the saliva was taken and diluted with phosphate buffered saline and then plated onto 5% sheep blood agar plates, which were incubated. Colony forming unit (CFU) was measured for the salivary bacterial counts.
Results: After application of PVI and CHX, all the experimental groups showed statistically significant decrease in CFU (P<0.01). Group 2 (PVI, 40 s) showed more significant reduction rate in CFU than group 4 (CHX, 40 s; P<0.01). Group 6 (PVI, 40 s, irrigated) showed more significant reduction rate than group 2 (PVI, 40 s; P<0.01). Group 2 (PVI, 40 s) showed more significant reduction rate than group 1 (PVI, 20 s; P<0.01).
Conclusion: Application of PVI for 40 seconds and mechanical irrigation with sterilized normal saline showed the best result among the 8 groups in terms of the reduction rate of salivary bacterial counts.
키워드
Povidone-iodine;Chlorhexidine;Irrigation;Bacteria
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